Hair Restoration with Acell and Platelet Rich Plasma (PRP)

 

How Does ACell + PRP Injection Therapy Work?

Patients who are good candidates for ACell + PRP Injection Therapy indicate they are not interested in surgery, want to prevent more hair loss, and are currently experiencing a lot of miniaturized hair. A non-surgical solution for hair restoration, ACell's MatriStem (ACell), is not a pharmaceutical or a drug, but a Medical Device sanctioned by the FDA for use in plastic and reconstructive surgery. Structurally, ACell is a biomatrix that repairs and remodels damaged tissue.

 

In hair restoration, ACell is combined with PRP (platelet rich plasma) and injected into the scalp. The application of ACell + PRP causes miniaturized hair follicles to become healthier and larger, producing more robust hair growth. ACell activates follicular progenitor cells (adult stem cells) and PRP is loaded with growth factors that promote rapid angiogenesis and localized cell growth. Effective for both male and female pattern hair loss, ACell + PRP has also regrown hair in alopecia areata, eyebrow hypotrichosis and other patient cases with non-hereditary hair loss.

An ACell+PRP treatment takes about 90 minutes to complete. First, a blood sample is obtained which is specially processed to produce the PRP. A local anesthetic is then administered to completely numb the scalp treatment area. If desired, a sedative can be administered (if the patient is not driving). The ACell and PRP are combined and then administered via a series of injections over the full scalp or in a localized treatment area such as the eyebrows or beard.

The recovery from ACell+PRP therapy is typically uneventful. Pain is easily managed in most cases with non-narcotic analgesic medication such as Ibuprofen. Some mild swelling of the forehead is occasionally seen 1-2 days after ACell+PRP injections. This is normal and will resolve in 48 hours. Avoiding vigorous activity is recommended until the swelling is gone. There is no other downtime or noticeable effects of the procedure. Patients can wash their hair normally immediately after the injections.

New hair growth can be seen as early as 2 months, but is typically evident between 4-8 months and will continue to improve up to a year after treatment. To date, results have been maintained without additional injections for up 2 years in many patients, but no long term data is yet available to conclude that ACell induced hair growth is permanent.

ACell is available in a micronized particulate that the doctor mixes with a PRP concentration. An initial blood draw provides the PRP that is separated and mixed with the ACell so it is suspended in the patient's own platelet rich plasma (PRP). After the scalp is completely numbed, the mixture is injected with a very fine gauge needle in a matrix pattern across the scalp, focused on thinning areas.

ACell+PRP therapy can treat cases of hair loss including:

  • Male Pattern Hair Loss – especially in the early stages of balding, or anytime there is a lot of miniaturized hair on the scalp
  • Female Pattern Hair Loss – at all stages of hair loss
  • Hypotrichosis (fine/reduced hairs) of the eyebrows or beard
  • Alopecia Areata, Alopecia Totalis
  • Metabolic causes of hair loss – iron deficiency and medication induced hair loss